Efficient Delivery and Nuclear Uptake Is Not Sufficient to Detect Gene Editing in CD34+ Cells Directed by a Ribonucleoprotein Complex

CD34+ cells are prime targets for therapeutic strategies for gene editing, because modified progenitor cells have the capacity to differentiate through an erythropoietic lineage. Although experimental advances have been reported, the associated experimental protocols have largely been less than clea...

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Detalles Bibliográficos
Autores principales: Modarai, Shirin R., Man, Dula, Bialk, Pawel, Rivera-Torres, Natalia, Bloh, Kevin, Kmiec, Eric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992347/
https://www.ncbi.nlm.nih.gov/pubmed/29858048
http://dx.doi.org/10.1016/j.omtn.2018.01.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992347/
https://www.ncbi.nlm.nih.gov/pubmed/29858048
http://dx.doi.org/10.1016/j.omtn.2018.01.013

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