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Cryptotanshinone Protects Cartilage against Developing Osteoarthritis through the miR-106a-5p/GLIS3 Axis

Cryptotanshinone (CTS) has emerged as an anti-inflammatory agent in osteoarthritis (OA). However, the molecular mechanism underlying its potent therapeutic effect on OA remains largely unknown. MicroRNAs (miRNAs) act as crucial regulators in maintaining cartilage homeostasis. To investigate whether...

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Detalles Bibliográficos
Autores principales: Ji, Quanbo, Qi, Dengbin, Xu, Xiaojie, Xu, Yameng, Goodman, Stuart B., Kang, Lei, Song, Qi, Fan, Zhongyi, Maloney, William J., Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992348/
https://www.ncbi.nlm.nih.gov/pubmed/29858052
http://dx.doi.org/10.1016/j.omtn.2018.02.001