The Endocannabinoid Reuptake Inhibitor WOBE437 Is Orally Bioavailable and Exerts Indirect Polypharmacological Effects via Different Endocannabinoid Receptors

Different anandamide (AEA) transport inhibitors show antinociceptive and antiinflammatory effects in vivo, but due to their concomitant inhibition of fatty acid amide hydrolase (FAAH) and overall poor bioavailability, they cannot be used unequivocally to study the particular role of endocannabinoid...

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Detalles Bibliográficos
Autores principales: Reynoso-Moreno, Inés, Chicca, Andrea, Flores-Soto, Mario E., Viveros-Paredes, Juan M., Gertsch, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992379/
https://www.ncbi.nlm.nih.gov/pubmed/29910713
http://dx.doi.org/10.3389/fnmol.2018.00180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992379/
https://www.ncbi.nlm.nih.gov/pubmed/29910713
http://dx.doi.org/10.3389/fnmol.2018.00180

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