Targeting Inflammatory T Helper Cells via Retinoic Acid-Related Orphan Receptor Gamma t Is Ineffective to Prevent Allo-Response-Driven Colitis

Intestinal graft-versus-host disease (GvHD) is a life-threatening, inflammatory donor T cell-mediated complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). In the light of the reported efficacy of interleukin-23 (IL-23)-blockade to mitigate syngeneic intestinal inflammation...

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Detalles Bibliográficos
Autores principales: Buchele, Vera, Abendroth, Benjamin, Büttner-Herold, Maike, Vogler, Tina, Rothamer, Johanna, Ghimire, Sakhila, Ullrich, Evelyn, Holler, Ernst, Neurath, Markus F., Hildner, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992389/
https://www.ncbi.nlm.nih.gov/pubmed/29910804
http://dx.doi.org/10.3389/fimmu.2018.01138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992389/
https://www.ncbi.nlm.nih.gov/pubmed/29910804
http://dx.doi.org/10.3389/fimmu.2018.01138

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