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Regulation of PD-L1: Emerging Routes for Targeting Tumor Immune Evasion

Immune checkpoint blockade therapies (ICBTs) targeting programmed cell death 1 (PD-1) and its ligand programmed death ligand-1 (PD-L1/B7-H1/CD274) have exhibited momentous clinical benefits and durable responses in multiple tumor types. However, primary resistance is found in considerable number of...

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Detalles Bibliográficos
Autores principales: Wang, Yiting, Wang, Huanbin, Yao, Han, Li, Chushu, Fang, Jing-Yuan, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992436/
https://www.ncbi.nlm.nih.gov/pubmed/29910728
http://dx.doi.org/10.3389/fphar.2018.00536