Inflammatory-Related P62 Triggers Malignant Transformation of Mesenchymal Stem Cells through the Cascade of CUDR-CTCF-IGFII-RAS Signaling

Inflammatory and autophagy-related gene P62 is highly expressed in most human tumor tissues. Herein, we demonstrate that P62 promotes human mesenchymal stem cells’ malignant transformation via the cascade of P62-tumor necrosis factor alpha (TNF-α)-CUDR-CTCF-insulin growth factor II (IGFII)-H-Ras sig...

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Detalles Bibliográficos
Autores principales: Xin, Xiaoru, Wang, Chen, Lin, Zhuojia, Xu, Jie, Lu, Yanan, Meng, Qiuyu, Li, Xiaonan, Yang, Yuxin, Zheng, Qidi, Gui, Xin, Li, Tianming, Pu, Hu, Xiong, Wujun, Li, Jiao, Jia, Song, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992448/
https://www.ncbi.nlm.nih.gov/pubmed/29858072
http://dx.doi.org/10.1016/j.omtn.2018.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992448/
https://www.ncbi.nlm.nih.gov/pubmed/29858072
http://dx.doi.org/10.1016/j.omtn.2018.03.002

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