Intradermal Delivery of Synthetic mRNA Using Hollow Microneedles for Efficient and Rapid Production of Exogenous Proteins in Skin

In recent years, synthetic mRNA-based applications to produce desired exogenous proteins in cells have been gaining importance. However, systemic delivery of synthetic mRNA can result in unspecific uptake into undesired cells or organs and, thereby, fail to target desired cells. Thus, local and targ...

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Detalles Bibliográficos
Autores principales: Golombek, Sonia, Pilz, Martin, Steinle, Heidrun, Kochba, Efrat, Levin, Yotam, Lunter, Dominique, Schlensak, Christian, Wendel, Hans Peter, Avci-Adali, Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992458/
https://www.ncbi.nlm.nih.gov/pubmed/29858073
http://dx.doi.org/10.1016/j.omtn.2018.03.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992458/
https://www.ncbi.nlm.nih.gov/pubmed/29858073
http://dx.doi.org/10.1016/j.omtn.2018.03.005

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