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Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury

After spinal cord injury (SCI), nerve regeneration is severely hampered due to the establishment of a highly inhibitory microenvironment at the injury site, through the contribution of multiple factors. The potential of antisense oligonucleotides (AONs) to modify gene expression at different levels,...

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Detalles Bibliográficos
Autores principales: Moreno, Pedro M.D., Ferreira, Ana R., Salvador, Daniela, Rodrigues, Maria T., Torrado, Marília, Carvalho, Eva D., Tedebark, Ulf, Sousa, Mónica M., Amaral, Isabel F., Wengel, Jesper, Pêgo, Ana P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992461/
https://www.ncbi.nlm.nih.gov/pubmed/29858074
http://dx.doi.org/10.1016/j.omtn.2018.03.009