Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons

Midbrain dopamine (DA) neurons are considered a critical substrate for the reinforcing and sensitizing effects of nicotine and tobacco dependence. While the role of the α4 and β2 subunit containing nicotinic acetylcholine receptors (α4β2(∗)nAChRs) in mediating nicotine effects on DA release and DA n...

Descripción completa

Detalles Bibliográficos
Autores principales: Collo, Ginetta, Cavalleri, Laura, Zoli, Michele, Maskos, Uwe, Ratti, Emiliangelo, Merlo Pich, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992464/
https://www.ncbi.nlm.nih.gov/pubmed/29910731
http://dx.doi.org/10.3389/fphar.2018.00572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992464/
https://www.ncbi.nlm.nih.gov/pubmed/29910731
http://dx.doi.org/10.3389/fphar.2018.00572

Ejemplares similares