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1α,25(OH)(2)D(3)-glycosides from Solanum glaucophyllum leaves extract induce myoblasts differentiation through p38 MAPK and AKT activation

We have previously shown that Solanum glaucophyllum leaf extract (SGE) increases VDR protein levels and promotes myoblast differentiation. Here, we investigated whether p38 MAPK and AKT are involved in SGE actions. Cell-cycle studies showed that SGE prompted a peak of S-phase followed by an arrest i...

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Detalles Bibliográficos
Autores principales: Irazoqui, Ana Paula, De Genaro, Pablo, Buitrago, Claudia, Bachmann, Heinrich, González-Pardo, Verónica, Russo de Boland, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992525/
https://www.ncbi.nlm.nih.gov/pubmed/29685991
http://dx.doi.org/10.1242/bio.033670