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Tolerance to paternal genotoxic damage promotes survival during embryo development in zebrafish (Danio rerio)

Spermatozoa carry DNA damage that must be repaired by the oocyte machinery upon fertilization. Different strategies could be adopted by different vertebrates to face the paternal genotoxic damage. Mammals have strong sperm selection mechanisms and activate a zygotic DNA damage response (DDR) (includ...

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Detalles Bibliográficos
Autores principales: Fernández-Díez, Cristina, González-Rojo, Silvia, Lombó, Marta, Herráez, M. Paz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992526/
https://www.ncbi.nlm.nih.gov/pubmed/29712649
http://dx.doi.org/10.1242/bio.030130