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Tolerance to paternal genotoxic damage promotes survival during embryo development in zebrafish (Danio rerio)
Spermatozoa carry DNA damage that must be repaired by the oocyte machinery upon fertilization. Different strategies could be adopted by different vertebrates to face the paternal genotoxic damage. Mammals have strong sperm selection mechanisms and activate a zygotic DNA damage response (DDR) (includ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992526/ https://www.ncbi.nlm.nih.gov/pubmed/29712649 http://dx.doi.org/10.1242/bio.030130 |