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Functional comparison of distinct Brachyury(+) states in a renal differentiation assay

Mesodermal populations can be generated in vitro from mouse embryonic stem cells (mESCs) using three-dimensional (3-D) aggregates called embryoid bodies or two-dimensional (2-D) monolayer culture systems. Here, we investigated whether Brachyury-expressing mesodermal cells generated using 3-D or 2-D...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Plagge, Antonius, Murray, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992531/
https://www.ncbi.nlm.nih.gov/pubmed/29666052
http://dx.doi.org/10.1242/bio.031799