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Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells

The purpose of this study was to devise a strategy for the derivation of corneal endothelial cells (CEnCs) from adult fibroblast-derived induced pluripotent stem cells (iPSCs). IPSCs were generated from an adult human with normal ocular history via expression of OCT4, SOX2, KLF4 and c-MYC. Neural cr...

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Detalles Bibliográficos
Autores principales: Wagoner, Michael D., Bohrer, Laura R., Aldrich, Benjamin T., Greiner, Mark A., Mullins, Robert F., Worthington, Kristan S., Tucker, Budd A., Wiley, Luke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992532/
https://www.ncbi.nlm.nih.gov/pubmed/29685994
http://dx.doi.org/10.1242/bio.032102