Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence

The hallmarks of age-related immune senescence are chronic inflammation, aberrant expansion of effector memory, and loss of naive T lymphocytes due in part to systemic activation of innate immune sensor NLRP3 inflammasome in myeloid lineage cells. The endogenous mechanisms that regulate inflammasome...

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Detalles Bibliográficos
Autores principales: Spadaro, Olga, Goldberg, Emily L., Camell, Christina D., Youm, Yun-Hee, Kopchick, John J., Nguyen, Kim Y., Bartke, Andrzej, Sun, Liou Y., Dixit, Vishwa Deep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992590/
https://www.ncbi.nlm.nih.gov/pubmed/26876170
http://dx.doi.org/10.1016/j.celrep.2016.01.044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992590/
https://www.ncbi.nlm.nih.gov/pubmed/26876170
http://dx.doi.org/10.1016/j.celrep.2016.01.044

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