Cargando…

Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence

The hallmarks of age-related immune senescence are chronic inflammation, aberrant expansion of effector memory, and loss of naive T lymphocytes due in part to systemic activation of innate immune sensor NLRP3 inflammasome in myeloid lineage cells. The endogenous mechanisms that regulate inflammasome...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spadaro, Olga, Goldberg, Emily L., Camell, Christina D., Youm, Yun-Hee, Kopchick, John J., Nguyen, Kim Y., Bartke, Andrzej, Sun, Liou Y., Dixit, Vishwa Deep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992590/ https://www.ncbi.nlm.nih.gov/pubmed/26876170 http://dx.doi.org/10.1016/j.celrep.2016.01.044

Ejemplares similares

AGING INDUCES NLRP3 INFLAMMASOME DEPENDENT ADIPOSE B CELL EXPANSION TO IMPAIR METABOLIC HOMEOSTASIS
por: Camell, Christina, et al.
Publicado: (2019)

Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis in the aged
por: Camell, Christina D., et al.
Publicado: (2017)

Nlrp3 Inflammasome Activation in Type 2 Diabetes: Is It Clinically Relevant?
por: Dixit, Vishwa Deep
Publicado: (2013)

Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity
por: Ryu, Seungjin, et al.
Publicado: (2023)

The NALP3/NLRP3 Inflammasome Instigates Obesity-Induced Autoinflammation and Insulin Resistance
por: Vandanmagsar, Bolormaa, et al.
Publicado: (2011)

Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease
por: Youm, Yun-Hee, et al.
Publicado: (2015)

Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation
por: Goldberg, Emily L., et al.
Publicado: (2017)

Inhibiting the NLRP3 Inflammasome
por: El-Sharkawy, Lina Y., et al.
Publicado: (2020)

The NLRP1 and CARD8 inflammasomes
por: Taabazuing, Cornelius Y., et al.
Publicado: (2020)

Mechanisms of disease: inflammasome activation and the development of type 2 diabetes
por: Grant, Ryan W., et al.
Publicado: (2013)

Do altered energy metabolism or spontaneous locomotion ‘mediate’ decelerated senescence?
por: Arum, Oge, et al.
Publicado: (2015)

Resveratrol Inhibits Ischemia-Induced Myocardial Senescence Signals and NLRP3 Inflammasome Activation
por: Feng, Hong, et al.
Publicado: (2020)

Innate immune cell-intrinsic ketogenesis is dispensable for organismal metabolism and age-related inflammation
por: Goldberg, Emily L., et al.
Publicado: (2023)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

Adipose Tissue Macrophages Are Innate to the Immunological Awareness of Adipose Tissue
por: Dixit, Vishwa Deep
Publicado: (2013)

The effects of early-life growth hormone intervention on tissue specific histone H3 modifications in long-lived Ames dwarf mice
por: Zhang, Fang, et al.
Publicado: (2020)

Neurodegenerative Disease and the NLRP3 Inflammasome
por: Holbrook, Jonathan A., et al.
Publicado: (2021)

Genistein Attenuates Acute Cerebral Ischemic Damage by Inhibiting the NLRP3 Inflammasome in Reproductively Senescent Mice
por: Wang, Shiquan, et al.
Publicado: (2020)

Honokiol antagonizes doxorubicin-induced cardiomyocyte senescence by inhibiting TXNIP-mediated NLRP3 inflammasome activation
por: Huang, Pian-Pian, et al.
Publicado: (2020)

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome
por: Menu, P, et al.
Publicado: (2011)

RAB20 deficiency promotes the development of silicosis via NLRP3 inflammasome
por: Peng, Zhouyangfan, et al.
Publicado: (2022)

Indoxyl Sulfate Mediates the Low Inducibility of the NLRP3 Inflammasome in Hemodialysis Patients
por: Ho, Li-Chun, et al.
Publicado: (2021)

The role of NLRP3 inflammasome for microglial response to peripheral inflammation
por: Garaschuk, Olga
Publicado: (2020)

Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging
por: Arum, Oge, et al.
Publicado: (2014)

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
por: Yang-Wei Fann, D, et al.
Publicado: (2013)

Research Progress of Mitochondrial Mechanism in NLRP3 Inflammasome Activation and Exercise Regulation of NLRP3 Inflammasome
por: Zhang, Tan, et al.
Publicado: (2021)

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease
por: Saresella, Marina, et al.
Publicado: (2016)

The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney
por: Kim, Yang Gyun, et al.
Publicado: (2019)

Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation
por: Shi, Lei, et al.
Publicado: (2019)

Sex-Specific Effects of the Nlrp3 Inflammasome on Atherogenesis in LDL Receptor-Deficient Mice
por: Chen, Shuang, et al.
Publicado: (2020)

Baicalin ameliorates atherosclerosis by inhibiting NLRP3 inflammasome in apolipoprotein E-deficient mice
por: Zhao, Jingfei, et al.
Publicado: (2020)

The role of the NLRP3 inflammasome in gout
por: Kingsbury, Sarah R, et al.
Publicado: (2011)

The Role of the NLRP3 Inflammasome in Fibrosis
por: Artlett, Carol M
Publicado: (2012)

NLRP3 Inflammasome and MS/EAE
por: Inoue, Makoto, et al.
Publicado: (2013)

NLRP3 Inflammasome and Pathobiology in AMD
por: Celkova, Lucia, et al.
Publicado: (2015)

Role of the NLRP3 inflammasome in cancer
por: Moossavi, Maryam, et al.
Publicado: (2018)

Spotlight on the NLRP3 inflammasome pathway
por: Groslambert, Marine, et al.
Publicado: (2018)

Regulation of NLRP3 Inflammasome by Phosphorylation
por: Song, Nan, et al.
Publicado: (2018)

Role of NLRP3 Inflammasomes in Atherosclerosis
por: Karasawa, Tadayoshi, et al.
Publicado: (2017)

NLRP3 inflammasome in endothelial dysfunction
por: Bai, Baochen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j1rf9bnic9l7mlehlata9q572s