Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation

The bone morphogenetic protein (BMP) signaling pathway, including antagonists, functions in lung development and regeneration of tracheal epithelium from basal stem cells. Here, we explore its role in the alveolar region, where type 2 epithelial cells (AT2s) and Pdgfrα(+) type 2-associated stromal c...

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Detalles Bibliográficos
Autores principales: Chung, Mei-I, Bujnis, Melissa, Barkauskas, Christina E., Kobayashi, Yoshihiko, Hogan, Brigid L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992594/
https://www.ncbi.nlm.nih.gov/pubmed/29752282
http://dx.doi.org/10.1242/dev.163014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992594/
https://www.ncbi.nlm.nih.gov/pubmed/29752282
http://dx.doi.org/10.1242/dev.163014

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