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Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation
The bone morphogenetic protein (BMP) signaling pathway, including antagonists, functions in lung development and regeneration of tracheal epithelium from basal stem cells. Here, we explore its role in the alveolar region, where type 2 epithelial cells (AT2s) and Pdgfrα(+) type 2-associated stromal c...
Autores principales: | Chung, Mei-I, Bujnis, Melissa, Barkauskas, Christina E., Kobayashi, Yoshihiko, Hogan, Brigid L. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992594/ https://www.ncbi.nlm.nih.gov/pubmed/29752282 http://dx.doi.org/10.1242/dev.163014 |
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