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Metabolic engineering of Acremonium chrysogenum for improving cephalosporin C production independent of methionine stimulation

BACKGROUND: Cephalosporin C (CPC) produced by Acremonium chrysogenum is one of the most important drugs for treatment of bacterial infectious diseases. As the major stimulant, methionine is widely used in the industrial production of CPC. In this study, we found methionine stimulated CPC production...

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Detalles Bibliográficos
Autores principales: Liu, Jiajia, Gao, Wenyan, Pan, Yuanyuan, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992653/
https://www.ncbi.nlm.nih.gov/pubmed/29879990
http://dx.doi.org/10.1186/s12934-018-0936-5