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Metabolic engineering of Acremonium chrysogenum for improving cephalosporin C production independent of methionine stimulation
BACKGROUND: Cephalosporin C (CPC) produced by Acremonium chrysogenum is one of the most important drugs for treatment of bacterial infectious diseases. As the major stimulant, methionine is widely used in the industrial production of CPC. In this study, we found methionine stimulated CPC production...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992653/ https://www.ncbi.nlm.nih.gov/pubmed/29879990 http://dx.doi.org/10.1186/s12934-018-0936-5 |