CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation

BACKGROUND: The reported antitumor activity of the BET family bromodomain inhibitors has prompted the development of inhibitors against other bromodomains. However, the human genome encodes more than 60 different bromodomains and most of them remain unexplored. RESULTS: We report that the bromodomai...

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Detalles Bibliográficos
Autores principales: Garcia-Carpizo, Veronica, Ruiz-Llorente, Sergio, Sarmentero, Jacinto, Graña-Castro, Osvaldo, Pisano, David G., Barrero, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992658/
https://www.ncbi.nlm.nih.gov/pubmed/29884215
http://dx.doi.org/10.1186/s13072-018-0197-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992658/
https://www.ncbi.nlm.nih.gov/pubmed/29884215
http://dx.doi.org/10.1186/s13072-018-0197-x

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