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CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation
BACKGROUND: The reported antitumor activity of the BET family bromodomain inhibitors has prompted the development of inhibitors against other bromodomains. However, the human genome encodes more than 60 different bromodomains and most of them remain unexplored. RESULTS: We report that the bromodomai...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992658/ https://www.ncbi.nlm.nih.gov/pubmed/29884215 http://dx.doi.org/10.1186/s13072-018-0197-x |