Gene Therapy for Neuropathic Pain through siRNA-IRF5 Gene Delivery with Homing Peptides to Microglia

Astrocyte- and microglia-targeting peptides were identified and isolated using phage display technology. A series of procedures, including three cycles of both in vivo and in vitro biopanning, was performed separately in astrocytes and in M1 or M2 microglia, yielding 50–58 phage plaques in each cell...

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Detalles Bibliográficos
Autores principales: Terashima, Tomoya, Ogawa, Nobuhiro, Nakae, Yuki, Sato, Toshiyuki, Katagi, Miwako, Okano, Junko, Maegawa, Hiroshi, Kojima, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992689/
https://www.ncbi.nlm.nih.gov/pubmed/29858055
http://dx.doi.org/10.1016/j.omtn.2018.02.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992689/
https://www.ncbi.nlm.nih.gov/pubmed/29858055
http://dx.doi.org/10.1016/j.omtn.2018.02.007

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