Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

BACKGROUND: Alzheimer’s disease (AD) is characterized by neuronal loss and astrocytosis in the cerebral cortex. However, the specific effects that pathological mutations and coding variants associated with AD have on the cellular composition of the brain are often ignored. METHODS: We developed and...

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Detalles Bibliográficos
Autores principales: Li, Zeran, Del-Aguila, Jorge L., Dube, Umber, Budde, John, Martinez, Rita, Black, Kathleen, Xiao, Qingli, Cairns, Nigel J., Dougherty, Joseph D., Lee, Jin-Moo, Morris, John C., Bateman, Randall J., Karch, Celeste M., Cruchaga, Carlos, Harari, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992755/
https://www.ncbi.nlm.nih.gov/pubmed/29880032
http://dx.doi.org/10.1186/s13073-018-0551-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992755/
https://www.ncbi.nlm.nih.gov/pubmed/29880032
http://dx.doi.org/10.1186/s13073-018-0551-4

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