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Activin A increases phagocytosis of Escherichia coli K1 by primary murine microglial cells activated by toll-like receptor agonists

BACKGROUND: Bacterial meningitis is associated with high mortality and long-term neurological sequelae. Increasing the phagocytic activity of microglia could improve the resistance of the CNS against infections. We studied the influence of activin A, a member of the TGF-β family with known immunoreg...

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Detalles Bibliográficos
Autores principales: Diesselberg, Catharina, Ribes, Sandra, Seele, Jana, Kaufmann, Annika, Redlich, Sandra, Bunkowski, Stephanie, Hanisch, Uwe-Karsten, Michel, Uwe, Nau, Roland, Schütze, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992782/
https://www.ncbi.nlm.nih.gov/pubmed/29880000
http://dx.doi.org/10.1186/s12974-018-1209-2