Development of a Reporter System to Explore MMEJ in the Context of Replacing Large Genomic Fragments

Common genome-editing strategies are either based on non-homologous end joining (NHEJ) or, in the presence of a template DNA, based on homologous recombination with long (homology-directed repair [HDR]) or short (microhomology-mediated end joining [MMEJ]) homologous sequences. In the current study,...

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Detalles Bibliográficos
Autores principales: Yanik, Mert, Ponnam, Surya Prakash Goud, Wimmer, Tobias, Trimborn, Lennart, Müller, Carina, Gambert, Isabel, Ginsberg, Johanna, Janise, Annabella, Domicke, Janina, Wende, Wolfgang, Lorenz, Birgit, Stieger, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992787/
https://www.ncbi.nlm.nih.gov/pubmed/29858075
http://dx.doi.org/10.1016/j.omtn.2018.03.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992787/
https://www.ncbi.nlm.nih.gov/pubmed/29858075
http://dx.doi.org/10.1016/j.omtn.2018.03.010

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