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S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease, characterized by damage of lung epithelial cells, excessive deposition of extracellular matrix in the lung interstitium, and enhanced activation and proliferation of fibroblasts. S100a4, also termed FSP-1 (fibroblast-spe...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Ohno, Shinji, Steer, Beatrix, Klee, Stephan, Staab-Weijnitz, Claudia A., Wagner, Darcy, Lehmann, Mareike, Stoeger, Tobias, Königshoff, Melanie, Adler, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992816/
https://www.ncbi.nlm.nih.gov/pubmed/29910813
http://dx.doi.org/10.3389/fimmu.2018.01216