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S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease, characterized by damage of lung epithelial cells, excessive deposition of extracellular matrix in the lung interstitium, and enhanced activation and proliferation of fibroblasts. S100a4, also termed FSP-1 (fibroblast-spe...
Autores principales: | Zhang, Wei, Ohno, Shinji, Steer, Beatrix, Klee, Stephan, Staab-Weijnitz, Claudia A., Wagner, Darcy, Lehmann, Mareike, Stoeger, Tobias, Königshoff, Melanie, Adler, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992816/ https://www.ncbi.nlm.nih.gov/pubmed/29910813 http://dx.doi.org/10.3389/fimmu.2018.01216 |
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