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H(1)-antihistamines are associated with lower prevalence of radiographic knee osteoarthritis: a cross-sectional analysis of the Osteoarthritis Initiative data

BACKGROUND: There is growing evidence that mast cells (MCs) play a role in knee osteoarthritis (OA). H(1)-antihistamines block H(1)-receptors of histamine, which is an important mediator of MCs. There is a lack of data on whether H(1)-antihistamines can influence OA. We hypothesized that the use of...

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Detalles Bibliográficos
Autores principales: Shirinsky, Ivan, Shirinsky, Valery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992840/
https://www.ncbi.nlm.nih.gov/pubmed/29880063
http://dx.doi.org/10.1186/s13075-018-1619-7