Manipulation of two regulatory genes for efficient production of chromomycins in Streptomyces reseiscleroticus

BACKGROUND: Regulatory genes play critical roles in natural product biosynthetic pathways. Chromomycins are promising anticancer natural products from actinomycetes. This study is aimed to create an efficient strain for production of these molecules by manipulating the regulatory genes. RESULTS: A p...

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Detalles Bibliográficos
Autores principales: Sun, Lei, Zeng, Jia, Cui, Peiwu, Wang, Wei, Yu, Dayu, Zhan, Jixun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992853/
https://www.ncbi.nlm.nih.gov/pubmed/29977332
http://dx.doi.org/10.1186/s13036-018-0103-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992853/
https://www.ncbi.nlm.nih.gov/pubmed/29977332
http://dx.doi.org/10.1186/s13036-018-0103-x

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