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The effect of different divalent cations on the kinetics and fidelity of Bacillus stearothermophilus DNA polymerase
Although Mg(2+) is the metal ion that functions as the cofactor for DNA polymerases (DNA pols) in vivo, Mn(2+) can also serve in this capacity but it reduces base discrimination. Metal ions aside from Mg(2+) or Mn(2+) can act as cofactors for some DNA pols but not for others. Here we report on the a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992921/ https://www.ncbi.nlm.nih.gov/pubmed/29888334 http://dx.doi.org/10.3934/biophy.2018.2.125 |