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Integrin CD11b negatively regulates Mincle-induced signaling via the Lyn–SIRPα–SHP1 complex

During mycobacteria infection, anti-inflammatory responses allow the host to avoid tissue damage caused by overactivation of the immune system; however, little is known about the negative modulators that specifically control mycobacteria-induced immune responses. Here we demonstrate that integrin CD...

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Detalles Bibliográficos
Autores principales: Zhang, Quanri, Lee, Wook-Bin, Kang, Ji-Seon, Kim, Lark Kyun, Kim, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992981/
https://www.ncbi.nlm.nih.gov/pubmed/29400702
http://dx.doi.org/10.1038/emm.2017.256