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The significance of intertumor and intratumor heterogeneity in liver cancer

Genomic analyses of primary liver cancer samples reveal a complex mutational landscape with vast intertumor and intratumor heterogeneity. Different primary liver tumors and subclones within each tumor display striking molecular and biological variations. Consequently, tumor molecular heterogeneity c...

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Detalles Bibliográficos
Autores principales: Liu, Jinping, Dang, Hien, Wang, Xin Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992990/
https://www.ncbi.nlm.nih.gov/pubmed/29303512
http://dx.doi.org/10.1038/emm.2017.165