Functional Consequences of the Postnatal Switch From Neonatal to Mutant Adult Glycine Receptor α1 Subunits in the Shaky Mouse Model of Startle Disease

Mutations in GlyR α1 or β subunit genes in humans and rodents lead to severe startle disease characterized by rigidity, massive stiffness and excessive startle responses upon unexpected tactile or acoustic stimuli. The recently characterized startle disease mouse mutant shaky carries a missense muta...

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Detalles Bibliográficos
Autores principales: Schaefer, Natascha, Zheng, Fang, van Brederode, Johannes, Berger, Alexandra, Leacock, Sophie, Hirata, Hiromi, Paige, Christopher J., Harvey, Robert J., Alzheimer, Christian, Villmann, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992992/
https://www.ncbi.nlm.nih.gov/pubmed/29910711
http://dx.doi.org/10.3389/fnmol.2018.00167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992992/
https://www.ncbi.nlm.nih.gov/pubmed/29910711
http://dx.doi.org/10.3389/fnmol.2018.00167

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