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Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway

INTRODUCTION: Colorectal cancer (CRC) is a major worldwide health problem owing to its high prevalence and mortality rate. Developments in screening, prevention, biomarker, personalized therapies and chemotherapy have improved detection and treatment. However, despite these advances, many patients w...

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Detalles Bibliográficos
Autores principales: Al-Obeed, Omar, Vaali-Mohammed, Mansoor-Ali, Eldehna, Wagdy M, Al-Khayal, Khayal, Mahmood, Amer, Abdel-Aziz, Hatem A, Zubaidi, Ahmed, Alafeefy, Ahmed, Abdulla, Maha, Ahmad, Rehan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993033/
https://www.ncbi.nlm.nih.gov/pubmed/29892198
http://dx.doi.org/10.2147/OTT.S148108