Cargando…
Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway
INTRODUCTION: Colorectal cancer (CRC) is a major worldwide health problem owing to its high prevalence and mortality rate. Developments in screening, prevention, biomarker, personalized therapies and chemotherapy have improved detection and treatment. However, despite these advances, many patients w...
Autores principales: | Al-Obeed, Omar, Vaali-Mohammed, Mansoor-Ali, Eldehna, Wagdy M, Al-Khayal, Khayal, Mahmood, Amer, Abdel-Aziz, Hatem A, Zubaidi, Ahmed, Alafeefy, Ahmed, Abdulla, Maha, Ahmad, Rehan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993033/ https://www.ncbi.nlm.nih.gov/pubmed/29892198 http://dx.doi.org/10.2147/OTT.S148108 |
Ejemplares similares
-
Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration
por: Al-Khayal, Khayal, et al.
Publicado: (2017) -
Identification of the TP53-induced glycolysis and apoptosis regulator in various stages of colorectal cancer patients
por: AL-KHAYAL, KHAYAL, et al.
Publicado: (2016) -
Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating β-catenin and increases irinotecan sensitivity in colorectal cancer
por: Abdulla, Maha, et al.
Publicado: (2022) -
Polymorphisms of tumor necrosis factor alpha in Middle Eastern population with colorectal cancer
por: Hamadien, Maha-Abdulla, et al.
Publicado: (2015) -
Differential expression of mucins in Middle Eastern patients with colorectal cancer
por: AL-KHAYAL, KHAYAL, et al.
Publicado: (2016)