Cargando…

ALPK2 Promotes Cardiogenesis in Zebrafish and Human Pluripotent Stem Cells

Cardiac development requires coordinated biphasic regulation of the WNT/β-catenin signaling pathway. By intersecting gene expression and loss-of-function siRNA screens we identified Alpha Protein Kinase 2 (ALPK2) as a candidate negative regulator of WNT/β-catenin signaling in cardiogenesis. In diffe...

Descripción completa

Detalles Bibliográficos
Autores principales: Hofsteen, Peter, Robitaille, Aaron Mark, Strash, Nicholas, Palpant, Nathan, Moon, Randall T., Pabon, Lil, Murry, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993047/
https://www.ncbi.nlm.nih.gov/pubmed/29888752
http://dx.doi.org/10.1016/j.isci.2018.03.010