A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles

Recent large-scale genome-wide association studies have identified tens of genetic loci robustly associated with Body Mass Index (BMI). Gene expression profiles were also found to be associated with BMI. However, accurate prediction of obesity risk utilizing genetic data remains challenging. In a co...

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Detalles Bibliográficos
Autores principales: Joseph, Paule V., Wang, Yupeng, Fourie, Nicolaas H., Henderson, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993110/
https://www.ncbi.nlm.nih.gov/pubmed/29795655
http://dx.doi.org/10.1371/journal.pone.0197843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993110/
https://www.ncbi.nlm.nih.gov/pubmed/29795655
http://dx.doi.org/10.1371/journal.pone.0197843

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