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Uncovering production of specialized metabolites by Streptomyces argillaceus: Activation of cryptic biosynthesis gene clusters using nutritional and genetic approaches

Sequencing of Streptomyces genomes has revealed they harbor a high number of biosynthesis gene cluster (BGC), which uncovered their enormous potentiality to encode specialized metabolites. However, these metabolites are not usually produced under standard laboratory conditions. In this manuscript we...

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Detalles Bibliográficos
Autores principales: Becerril, Adriana, Álvarez, Susana, Braña, Alfredo F., Rico, Sergio, Díaz, Margarita, Santamaría, Ramón I., Salas, José A., Méndez, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993118/
https://www.ncbi.nlm.nih.gov/pubmed/29795673
http://dx.doi.org/10.1371/journal.pone.0198145