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Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer

Cancer cells often upregulate nutrient transporters to fulfill their increased biosynthetic and bioenergetic needs, and to maintain redox homeostasis. One nutrient transporter frequently overexpressed in human cancers is the cystine/glutamate antiporter solute carrier family 7 member 11 (SLC7A11; al...

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Detalles Bibliográficos
Autores principales: Koppula, Pranavi, Zhang, Yilei, Zhuang, Li, Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993148/
https://www.ncbi.nlm.nih.gov/pubmed/29764521
http://dx.doi.org/10.1186/s40880-018-0288-x