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EYA4 inhibits hepatocellular carcinoma growth and invasion by suppressing NF-κB-dependent RAP1 transactivation

BACKGROUND: Our previous studies demonstrated that eyes absent homolog 4 (EYA4), a member of the eye development-related EYA family in Drosophila, is frequently methylated and silenced in hepatocellular carcinoma (HCC) specimens and associated with shorter survival. The current work aimed to explore...

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Detalles Bibliográficos
Autores principales: Mo, Shi-Jing, Hou, Xun, Hao, Xiao-Yi, Cai, Jian-Peng, Liu, Xin, Chen, Wei, Chen, Dong, Yin, Xiao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993152/
https://www.ncbi.nlm.nih.gov/pubmed/29764501
http://dx.doi.org/10.1186/s40880-018-0276-1