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Functional Modulation of Gene Expression by Ultraconserved Long Non-coding RNA TUC338 during Growth of Human Hepatocellular Carcinoma

TUC338 is an ultraconserved long non-coding RNA that contributes to transformed cell growth in hepatocellular carcinoma (HCC). Genomic regions of TUC338 occupancy were enriched in unique or known binding motifs homologous to the tumor suppressors Pax6 and p53. Genes involved in cell proliferation we...

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Detalles Bibliográficos
Autores principales: Wen, Hui-Ju, Walsh, Michael P., Yan, Irene K., Takahashi, Kenji, Fields, Alan, Patel, Tushar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993207/
https://www.ncbi.nlm.nih.gov/pubmed/29888750
http://dx.doi.org/10.1016/j.isci.2018.03.004