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Effects of smoking and body mass index on the exposure of fentanyl in patients with cancer

The transdermal fentanyl patch is widely used to treat cancer-related pain despite its wide inter- and intrapatient variability in pharmacokinetics. The aim of this study was to investigate whether smoking and body size (i.e. body mass index) influence fentanyl exposure in patients with cancer. Thes...

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Detalles Bibliográficos
Autores principales: Kuip, Evelien J. M., Oldenmenger, Wendy H., Thijs—Visser, Martine F., de Bruijn, Peter, Oosten, Astrid W., Oomen—de Hoop, Esther, Koolen, Stijn L. W., Van der Rijt, Carin C. D., Mathijssen, Ron H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993275/
https://www.ncbi.nlm.nih.gov/pubmed/29883454
http://dx.doi.org/10.1371/journal.pone.0198289