Differential strengths of molecular determinants guide environment specific mutational fates

Organisms maintain competitive fitness in the face of environmental challenges through molecular evolution. However, it remains largely unknown how different biophysical factors constrain molecular evolution in a given environment. Here, using deep mutational scanning, we quantified empirical fitnes...

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Detalles Bibliográficos
Autores principales: Dandage, Rohan, Pandey, Rajesh, Jayaraj, Gopal, Rai, Manish, Berger, David, Chakraborty, Kausik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993328/
https://www.ncbi.nlm.nih.gov/pubmed/29813059
http://dx.doi.org/10.1371/journal.pgen.1007419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993328/
https://www.ncbi.nlm.nih.gov/pubmed/29813059
http://dx.doi.org/10.1371/journal.pgen.1007419

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