Cargando…
Differential strengths of molecular determinants guide environment specific mutational fates
Organisms maintain competitive fitness in the face of environmental challenges through molecular evolution. However, it remains largely unknown how different biophysical factors constrain molecular evolution in a given environment. Here, using deep mutational scanning, we quantified empirical fitnes...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993328/ https://www.ncbi.nlm.nih.gov/pubmed/29813059 http://dx.doi.org/10.1371/journal.pgen.1007419 |