Cargando…

Continuous DNA replication is required for late gene transcription and maintenance of replication compartments in gammaherpesviruses

Late gene transcription in herpesviruses is dependent on viral DNA replication in cis but the mechanistic basis for this linkage remains unknown. DNA replication results in demethylated DNA, topological changes, removal of proteins and recruitment of proteins to promoters. One or more of these effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Dajiang, Fu, Wenmin, Swaminathan, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993329/
https://www.ncbi.nlm.nih.gov/pubmed/29813138
http://dx.doi.org/10.1371/journal.ppat.1007070