Polymorphic factor H-binding activity of CspA protects Lyme borreliae from the host complement in feeding ticks to facilitate tick-to-host transmission

Borrelia burgdorferi sensu lato (Bbsl), the causative agent of Lyme disease, establishes an initial infection in the host’s skin following a tick bite, and then disseminates to distant organs, leading to multisystem manifestations. Tick-to-vertebrate host transmission requires that Bbsl survives dur...

Descripción completa

Detalles Bibliográficos
Autores principales: Hart, Thomas, Nguyen, Ngoc Thien Thu, Nowak, Nancy A., Zhang, Fuming, Linhardt, Robert J., Diuk-Wasser, Maria, Ram, Sanjay, Kraiczy, Peter, Lin, Yi-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993331/
https://www.ncbi.nlm.nih.gov/pubmed/29813137
http://dx.doi.org/10.1371/journal.ppat.1007106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993331/
https://www.ncbi.nlm.nih.gov/pubmed/29813137
http://dx.doi.org/10.1371/journal.ppat.1007106

Ejemplares similares