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Coupled feedback loops maintain synaptic long-term potentiation: A computational model of PKMzeta synthesis and AMPA receptor trafficking

In long-term potentiation (LTP), one of the most studied types of neural plasticity, synaptic strength is persistently increased in response to stimulation. Although a number of different proteins have been implicated in the sub-cellular molecular processes underlying induction and maintenance of LT...

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Detalles Bibliográficos
Autores principales: Helfer, Peter, Shultz, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993340/
https://www.ncbi.nlm.nih.gov/pubmed/29813048
http://dx.doi.org/10.1371/journal.pcbi.1006147