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Anti-CD19 chimeric antigen receptor targeting of CD19 + acute myeloid leukemia

Aberrant expression of CD19 in acute myeloid leukemia (AML) is commonly associated with t(8;21)(q22;q22), although AML cases lacking this translocation occasionally express CD19. Mixed-phenotype acute leukemia also frequently expresses CD19. Chimeric antigen receptor (CAR) technology is a major brea...

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Detalles Bibliográficos
Autores principales: Ma, Gina, Wang, Yi, Ahmed, Tahmeena, Zaslav, Ann-Leslie, Hogan, Laura, Avila, Cecilia, Wada, Masayuki, Salman, Huda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993359/
https://www.ncbi.nlm.nih.gov/pubmed/29892548
http://dx.doi.org/10.1016/j.lrr.2018.03.002