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Anti-CD19 chimeric antigen receptor targeting of CD19 + acute myeloid leukemia
Aberrant expression of CD19 in acute myeloid leukemia (AML) is commonly associated with t(8;21)(q22;q22), although AML cases lacking this translocation occasionally express CD19. Mixed-phenotype acute leukemia also frequently expresses CD19. Chimeric antigen receptor (CAR) technology is a major brea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993359/ https://www.ncbi.nlm.nih.gov/pubmed/29892548 http://dx.doi.org/10.1016/j.lrr.2018.03.002 |