Proangiogenic Interactions of Vascular Endothelial MMP14 With VEGF Receptor 1 in VEGFA-Mediated Corneal Angiogenesis

PURPOSE: Matrix metalloproteinase 14 (MMP14) has been shown to be required for corneal angiogenesis. We hypothesized that the proangiogenic activity of MMP14 may be based on its selective binding to, and cleaving of, vascular endothelial growth factor receptor 1 (VEGFR1), but not VEGFR2 or VEGFR3. M...

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Detalles Bibliográficos
Autores principales: Han, Kyu-Yeon, Chang, Jin-Hong, Lee, Hyun, Azar, Dimitri T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993529/
https://www.ncbi.nlm.nih.gov/pubmed/27327585
http://dx.doi.org/10.1167/iovs.16-19420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993529/
https://www.ncbi.nlm.nih.gov/pubmed/27327585
http://dx.doi.org/10.1167/iovs.16-19420

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