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A novel dynamic multicellular co-culture system for studying individual blood-brain barrier cell types in brain diseases and cytotoxicity testing

Blood brain barrier (BBB) cells play key roles in the physiology and pathology of the central nervous system (CNS). BBB dysfunction is implicated in many neurodegenerative diseases, including Alzheimer’s disease (AD). The BBB consists of capillary endothelial cells, pericytes encircling the endothel...

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Detalles Bibliográficos
Autores principales: Miranda-Azpiazu, Patricia, Panagiotou, Stavros, Jose, Gin, Saha, Sikha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993789/
https://www.ncbi.nlm.nih.gov/pubmed/29884831
http://dx.doi.org/10.1038/s41598-018-26480-8